Defence potion(2)

Defence Potion(2) is a members-only item on the OSRS Grand Exchange in the potions category.

In-game examine text: "2 doses of Defence potion."

It has a Grand Exchange buy limit of 2,000 every four hours, a high alchemy value of 54 gp, and item ID 135.

View on OSRS Wiki

Defence Potion(2) shows an active flip setup with a margin of +158 gp and 4,482 trades over the last 24 hours.

At the buy limit of 2,000 every four hours, max profit per cycle is about 316.0k gp — high margin with healthy liquidity.